BICH 410 Lecture Notes - Lecture 6: Heptad Repeat, Robert Corey, Beta Bulge

• School: Texas A&M University
• Department: Biochemistry
• Course: BICH 410
• Professor: Chavela M Carr

Document Summary

P rote in cha in mus t a void loca l e ne rgy minima (tra ppe d s ta te s ) Firs t, we "ll look a t known prote in s tructure s to le a rn rule s. S tructure de pe nds on s e que nce a nd on we a k, noncova le nt force s. P rote in s tructure a nd function a re tightly linke d: the numbe r of prote in folding pa tte rns is la rge but finite. S tructure s of globula r prote ins a re ma rgina lly ta ble (de lta h ~ de lta. S : ma rgina l s ta bility fa cilita te s motion, motion e na ble s function, primary. Four le ve ls of prote in s tructure : cova le nt conne ctions.