PSY 446 Lecture Notes - Lecture 11: Hydroxycarbamide, Caffeine, Morphine

• School: Syracuse University
• Department: Psychology
• Course: PSY 446
• Professor: S. Sweeney

Document Summary

A genetic condition in which red blood cells are sickle-shaped. Figure b shows abnormal, sickled red blood cells clumping and blocking the blood flow in a blood vessel. The inset image shows a cross-section of a sickled red blood cell with abnormal strands of hemoglobin. Co(cid:374)ditio(cid:374) i(cid:374) whi(cid:272)h a perso(cid:374)"s (cid:271)lood has a lower tha(cid:374) (cid:374)or(cid:373)al (cid:374)u(cid:373)(cid:271)er of red (cid:271)lood (cid:272)ells. Sickle cells die faster than normal red blood cells. Approximately 100,000 americans have sickle cell disease. 1 in 13 black babies is born with sickle cell trait. 95% of children will live beyond age 18. Life expectancy in us has increased to 40-60 yrs. (avg. ) The vaso-occlusive crisis (voc) (cid:862)si(cid:272)kle (cid:272)ell (cid:272)risis(cid:863); a(cid:374) atta(cid:272)k of a(cid:272)ute pai(cid:374) Chronic pain: may be due to accumulation of organ/tissue damage over time. Patie(cid:374)t"s self-report is the gold-standard by which a voc is identified. Acetaminophen, nsaids, and narcotics (morphine, oxycodone, etc).