NURS 4390 Lecture Notes - Lecture 3: Orthostatic Hypotension, Benign Prostatic Hyperplasia, Adrenergic Agonist
3 May 2020
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Document Summary
Drugs currently available for treating htn have two main actions: decrease the volume of circulating blood, decrease svr. Monitor for orthostatic hypotension, hypokalemia, and alkalosis. Thiazide may potentiate cardiotoxicity of digoxin by producing hypokalemia. Nsaids can decrease diuretics and antihypertensive effect renal impairment. Monitor for orthostatic hypotension and electrolyte abnormalities. Use with caution in pts with ace inhibitors or angiotensin ii blockers. Sudden discontinuation may cause withdrawal syndrome: rebound htn, tachycardia, headache, tremors, sweating. Reduced resistance to the outflow of urine in benign prostatic hyperplasia. Taking drug at bedtime reduces risks associated with orthostatic hypotension. Use with caution in pts with diabetes because drugs may depress tachycardia. Inhibit nacl reabsorption in the ascending limb of the loop of henle. Triamterene exchange in the distal and collecting tubules. Inhibit the na+ retaining and k+ excreting effects of aldosterone in the distal and collecting tubules. Block alpha-1 adrenergic effects, producing peripheral vasodilation (decreases svr and. Reduce bp by blocking b1- adrenergic effects.
