PSY 359 Lecture Notes - Lecture 11: Taxis, Harm Avoidance, Model Organism
27 Oct 2016
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Face validity-seeing if it looks like the illness we are trying to model. 8arm-alzheimer"s and learning deficits(autism), schizophrenia drug side effect impairing memory. The elevated plus test-put rat in middle and an animal should choose to spend more time in the enclosed space. not afraid of predators. Typical animal will spend more time in enclosed but sometimes on the outside too. Light dark test- an animal prefers to be in dark place because of feeling safer. This test is also a commonly used model for anxiety. Putting unusual object in the box, how close will it go towards it. Typical time/approach- an animal that takes too short of a period time to approach shows deficits in harm avoidance**** One of major causes of death in autism is drowning* Open field behavior- big open field with squares marked on bottom of it and count to see how much time the animal spends in the middle of the field and along the wall.
