PSY 356 Lecture Notes - Lecture 4: Rapid Eye Movement Sleep, Amygdala, Cholinergic

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Dopamine: located in the, substantia nigra (sn) (in the ventral midbrain, projects to the caudate-putamen (mesenchephalon, ventral tegmental area (vta, projects to the nucleus accumbens (v), limbic system, and cortex (mainly frontal cortex) Mesostriatal pathway: arises from sn and projects to the caudate-putamen. Mesolimbic pathway: arises from the vta and projects to limbic structures (amygdala, hippocampus) Mesocortical pathway: arises from the vta and projects to the prefrontal cortex. It is caused by lesions in the basal pons: this lesion interrupts motor pathways from the cortex to the brainstem and spinal cord (corticospinal tract, the person"s eye movements are intact and communicate by blinking. Sleep: all neurotransmitters we talk about (ne, acetylcholine, serotonin) are involved in the neurophysiology of sleep, except for dopamine. They took measurements taken in a sleep lab. Measurements/tests taken: electromyogram (emg) of the neck muscles, electrooculogram (eog) of eye muscles, electrocardiogram (ekg, galvanic skin response (gsr, measure of respiration rate, electroencephalogram (eeg) of brain.

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