PSY 346 Lecture Notes - Lecture 5: Antigen-Presenting Cell, Natural Killer Cell, Tattletales

• School: Stony Brook University
• Department: Psychology
• Course: PSY 346
• Professor: Johanna Jarcho

Document Summary

Psycho: beliefs, thoughts, stress, emotions, moods, etc: classical conditioning. Sugar water + saline injection no nausea. Overview of the stress response: autonomic nervous system, hypothalamic pituitary adrenocortical axis. Primary job: defend the body against infectious agents like viruses, bacteria, parasites. Type 1 diabetes: attacks cells that secrete insulin. Autoimmune diseases: immune system starts attacking the body. Two types of immunity: innate immunity, specific (adaptive) immunity: It"s (cid:374)o(cid:374)spe(cid:272)ifi(cid:272) (cid:894)respo(cid:374)ds to all pathoge(cid:374)s i(cid:374) the sa(cid:373)e (cid:449)ay(cid:895) Cells of innate immunity: soldiers: natural killer cells, pac-men: macrophages, tattle tales: antigen presenting cells, ui(cid:272)ide bo(cid:373)(cid:271)ers: the (cid:862)phils(cid:863) Eosinophils: activated when there is a parasitic infection. Neutrophils: activated when there is a bacterial/fungal infection. Kill all invaders in the same way: nk ell releases perforins, which polymerize and form a hole. They kill by eating invaders and digesting them into harmless bits. Find the helper t cell that can bond to the antigen. They use antibodies (specially designed poison) to kill their victims.