PSY 250 Lecture Notes - Lecture 3: Sodium Channel, Membrane Potential, Psychopharmacology

• School: Stony Brook University
• Department: Psychology
• Course: PSY 250
• Professor: Ryan Parsons

Document Summary

Generation and conduction of neural impulses: postsynaptic potential, neural communication. What happens if you block sodium channels: tetrodotoxin (ttx, potent neurotoxin that blocks sodium channels. What happens if you block sodium channels: lidocaine, commonly used topical anesthetic that blocks sodium channels. Multiple sclerosis: a demyelinating condition in the cns, disruption of neural signal transmission. It is where one neuron communicates with another: 1. Key events of the synapse: exocytosis process of neurotransmitter release, 1) synaptic vesicles with the presynaptic membrane, 2) nt"s are released into the synaptic cleft, depends on the activity of calcium ions (ca++, 1. Ap reaching the axon terminal opens voltage- gated ca++ channels allowing ca++ into the terminal: 2. D1,d2,d3,d4,d5: the receptor subtypes are located in different areas of the brain, what advantage is there to having many different subtypes of receptor, a single transmitter can have a variety of, classification of receptors effects flexibility, 1. Ionotropic direct and fast acting: ligand-gated ion channels, 2.