HP 127 Lecture Notes - Lecture 8: Cardiac Muscle, Afterload, Cardiac Output

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Disastole: relaxation (spend more time in diastole than in systole- the slower the heart rate, more time) 3 main phases of the cardiac cycle: ventricular filling: takes place in mid-to-late diastole, ventricular systole, isovolumetric relaxation: early diastole. As the ventricles fill, not a lot of increase in pressure > heart is expanding. Pressure increases- contract, but no change in volume: pressure increase (isovolumetric contraction phase) Ventricular ejection phase- after ventricles are completely filled (edv- End diastolic volume), valves open (pressure is higher in the ventricles than in the blood vessels- aorta/pulmonary trunk), blood is ejected from the ventricles ventricular volume decreases. Esv: end systolic volume: amount of blood left in heart at the end of systole. Isovolumetric relaxation- early diastole, ventricular volume does not increase or decrease- no change. During ivr phase, av valves are closed blood is not flowing into ventricles and changing the volume- if there"s no change in volume, the valves are.

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