PHS 4601 Lecture Notes - Lecture 3: Propranolol, Rifampicin, Aspirin
Document Summary
4. 1 definition of capsules: solid dosage forms in which the drug is enclosed within either a hard or a soft soluble container or shell. The shells are usually formed from gelatin; however, they also may be made from starch or other suitable substances. Soft gelatin capsules- elasticity agent (glycerin) is added to make it soft. Easy to handle/carry as compared to powder/granule dosage forms. Easy to identify (color)- capsule shells come in different size, shape, color, etc. Mask taste due to shell containing drug. Hard to mask taste on powders, suspensions, etc. since the use of flavors and scents are required. Separate incompatible compounds- if 2 compounds are not compatible, put 1 into smaller capsule and then capsule plus other ingredients is used with a bigger capsule. Can also using granules and coatings to separate incompatible drugs in the same capsule. Easy to make - can be made by hand or via simple devices.