PHR 4111 Lecture Notes - Lecture 7: Sympatholytic, Cardiac Output, Sodium Nitroprusside
4 Dec 2017
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Document Summary
It"s all about the blood pressure equation !!!!! Output resistance: heart rate, contractility arteriolar volume, filling pressure vascular tone. Hypertension results in arteriolar vessel damage which is initially asymptomatic or silent until symptoms occur exhibited as end organ damage : Brain = cerbral strokes kidneys = uremia and renal failure. Figure 11-13 the critical roles of cardiac output and peripheral resistance in blood pressure regulation. Downloaded from: robbins & cotran pathologic basis of disease (on 6 november 2006 08:50 am) Co = stoke volume x hr (one parameter) Thought to be associated with sympathetic over activity. Mid to late stages: secondary to end organ damage=renal, +/- angio ii, +/- aldosterone/adh. Late htn diuretics & beta blocker effective with many adr"s. Bp = co (sv x hr) x pr. The role of the kidney in htn ,angiotensin ii and. Renal attack: (first because all anti ht drugs cause edema) Inhibit ras system (inhibiting angiotensin ii & aldosterone):
