BIOL 304 Lecture Notes - Lecture 1: Polytomy, Beta Particle, Motoo Kimura
Document Summary
Is killing the host a good strategy for a pathogen: answer lies in details of transmission and disease progression. Evolves faster than our immune system can work. Our "secondary response and memory t cells don"t work next season, because then the virus epitope has mutated. Evolution that happened in the past affects (and constraints) future evolution. Evolution moves a population towards a local optimum (not a global optimum) Our cells have a protein that blocks retrovirus replication. Evolution of the virus: developed resistence to drugs, sloppy dna replication, epitope evolves in an arms race with our immune system, its reverse transcriptase. Pattern of evolution and history of evolutionary thought. Most biologists thought species were distinct and unchanging. Most (western) geologists used young earth, biblical flood to explain rock layers, patterns of fossil occurrence. 1/26/2015 10:02:00 pm evolutionary bio has developed immensely since darwin"s work. Modern synthesus 20th century integration of darwin ideas with genetics.
