GEN S 340 Lecture Notes - Lecture 5: Tuberculosis, Esophagitis, Staphylococcus
Document Summary
Opportunistic infections: t4 or cd4+ < 200/ l, us 500,000, worldwide 12-18 million, oi"s were diagnosed in 33% in one year and 58% at two years after cd4 cell fell below 200. Pcp dropped from 80% (1987) to 20% (1994) Hiv co-infections: us, 95% - herpes 1 and/or 2, 40% - hepatitis c (causes psoriasis and liver problems) Monday, october 2, 2017: 36% - tb. Most common opportunistic infections: >100 organisms can cause ois, 6 most common, bacterial pneumonia, candidal esophagitis (yeast, pulmonary/disseminated tb, mycobacterium avium complex disease (mac, herpes simplex reinfection, pcp. Fungal diseases: healthy people have high innate resistance to fungal infections, most devastating, highly regional, high probability of recurrence. Histoplasmosis: breathe spores endemic in ms and oh river valleys, symptoms, in uenza like symptoms, shortness of breath, night sweats, chills, mouth sores. Monday, october 2, 2017: red skin bumps, initial oi in 2/3 of aids patients.
