ENS 333 Lecture Notes - Lecture 13: Thrombin, Coumarin, Antihypertensive Drug

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Most recovery occurs in week 1-2 following ischemic stroke: swelling subsides, injuries/deficits may resolve spontaneously depending on severity, these are reversible ischemic neurological deficits . Residual impairments may lead to permanent disability. 14% of patients surviving stroke/tia will have another within 1 year. However, all dependent on infarct size, time to treatment, severity of edema/swelling and rise of. Impairments usually less severe than hemorrhagic stroke intracranial pressure. Late prognosis worse with comorbidities: atrial fibrillation and/or diabetes mellitus, high risk for recurrent stroke. Rate of functional return is slower than hemorrhagic stroke (assuming survival of hemorrhage) Prognosis substantially worse when gcs < 9: scale for eye, verbal, and motor responses. Early mortality very high (~50% in the first month) Late prognosis is good, partly a selection bias issue (have to survive it to have a late prognosis) November 16, 2016: at home or on the street. Detection critical; time is of the essence.

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