ENS 333 Lecture Notes - Lecture 8: Renal Function, Chronic Kidney Disease, Peritoneal Dialysis

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Early adopter of using microscopy and histology for diagnosis and study. Early work was striated muscle, but by age 25 discovered and described what is now known as. Acute kidney injury (aka acute renal failure) Prognosis: it depends : underlying etiology, duration of acute kidney injury (aki) Patients are usually in the icu: associated comorbidities and severity of aki. In addition: risk of dying after hospital discharge higher with aki cases, even if the kidney function returns to normal, persons with aki history are at greater risk. Conceptual model for aki for chronic kidney disease (ckd) Creatinine is a product that is readily filtered, which ends up in the urine: good indicator of kidney function, high creatinine in serum not being filtered in the kidney. Due to no blood flow to the kidney (prerenal failure) or intrinsic renal damage (damage within the kidney itself: creatine is produced due to large storage in skeletal muscle.

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