ENS 333 Lecture Notes - Lecture 2: Diastolic Heart Failure, Heart Failure, Ejection Fraction
Document Summary
Mitochondrial density is related to the maximum oxidative capacity. The number of capillaries is also related to the maximum oxidative capacity. Calculated importance" of changes to key to transport variables on: qt = thoracic blood flow/cardiac output, dl = diffusion capacity in the lung, dm = diffusion value in a muscle. Controlled by mitochondrial density and capillary-to-fiber ratio: [hb] = concentration of hemoglobin, vastpd = alveolar ventilation. Computer modeling suggests that: 50% increase in q, 2% increase in, 50% increase in , 1% increase in, 50% increase in dm, 8% increase in. Moving right on the plot improvement. Moving left on the plot no improvement. I knew one who set himself a task of sawing wood for half an hour every day, and was nearly cured. The symptoms of debility of the heart are often removable by a regulated course of gymnastics, or by pedestrian exercise 1854. The prescription at his time was absolute bedrest.