ENS 333 Lecture Notes - Lecture 1: Fick'S Laws Of Diffusion, Cardiac Output, Relative Risk

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Relative risk of death is stratified based on oxidative capacity (in picture above) Fick equation how we calculate a rate of oxygen uptake. September 12, 2016: = rate of cardiac output (oxygen delivery, = difference between the arterial and venous blood; extraction of blood. Cardiac output is related to the maximum oxygen uptake linearly. Extraction is the ratio between delivery and uptake: deliver amount of take a bit of out have a little left over for the venous side. At 1 l of uptake, there is ~10 ml per dl of in the venous blood: ratio between cardiac output and uptake that determines value in the venous capillary. Interaction between convective and diffusive components for oxygen transport: convection and diffusion of oxygen interact with one another that set the maximal. Convection flow of blood down to the muscle (mass blood flow) Diffusion oxygen moving from the muscle to the capillaries.

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