ENS 332 Lecture Notes - Lecture 8: Ventricle (Heart), Second-Degree Atrioventricular Block, First-Degree Atrioventricular Block
11 Jan 2017
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Document Summary
Volume overload leads to diastolic wall stress series addition of myofibrils eccentric remodeling. If the chamber enlarges at the same amount as volume and pressure, then it should provide negative feedback and stem the increase in diastolic pressure: rarely happens would be a perfect situation. Left ventricular end diastolic pressure (lvedp: at the end of diastole, pressure in the heart is low. Heart is relaxed still filling and generates a little pressure: there is a certain stroke volume (sv) of ~70 ml. If venous return is reduced, there is a decrease in stroke volume. If venous return is increased, there is an increase in stroke volume. Stoke volume is very sensitive to changes in edv: an increase in lvedp results in a large increase in sv (steeper slope) In heart failure, the relationship is very flat. Keep the heart filling high pressure and volume at the end of diastole: eccentric remodeling.
