11:709:255 Lecture Notes - Lecture 16: Viral Hepatitis, Blood Transfusion, Hepatitis
3 Feb 2020
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Types a, b, c, d, and e. Hepatitis a (hav: transmission: oral fecal route via contaminated drinking water, sewage, food, concentration: feces, serum, saliva, prevention: vaccination, recovery often complete. Hepatitis d: transmission via blood and body fluids, only infects individuals with hbv, rare in the us. Hepatitis e: transmission via oral-fecal route (water, rate in us. Liver diseases of unspecified etiology unrelated to alcohol intake, evidenced by abnormal liver enzyme tests and fatty acid accumulation in the liver. Dx via imaging (i. e. ultrasound) or histology. Spectrum of nafld: fatty liver: fat accumulates in the liver, nash (nonalcoholic steatohepatitis: fat plus inflammation and scarring, cirrhosis: scar tissues replace liver cells. Risk factors and causes of nafld: primary, central obesity, metabolic syndrome, t2dm, hypertriglyceridemia, secondary, high intake of high fructose corn syrup, high intake saturated fat, surgical stress, medications, environmental toxins, viral hepatitis. Betaine: may increase lipoprotein transport and cell integrity decreased enzymes, steatosis, inflammation and fibrosis.
