01:146:328 Lecture Notes - Lecture 22: Toxocara Cati, Toxocariasis, Pyrantel
Document Summary
Discovered: paget and r. owen first discovered larvae of trichinella in a piece of human muscle during an autopsy. That same year, r. virchow and f. zenker discovered the complicated life cycle of trichinella by feeding a dog trichinella-infected meat. One-way digestive tract, with a pseudocoelom: life cycle: Trichinellosis is acquired by ingesting meat containing cysts (encysted larvae) of trichinella. After 1 week, the females release larvae that migrate to the striated muscles where they encyst. Trichinella pseudospiralis, however, does not encyst: pathology: Encystment is completed in 4 to 5 weeks and the encysted larvae may remain viable for several years. Ingestion of the encysted larvae perpetuates the cycle: diagnosis: The first evidence of pinworm infection dates back to roman-occupied egypt (30 bc-ad 395) also known as threadworm or seatworm. The eggs are then somehow ingested through many different ways. Following ingestion of infective eggs, the larvae hatch in the small intestine and the adults establish themselves in the colon.