01:146:328 Lecture Notes - Lecture 4: Sponge, Necrosis, Immunoglobulin Heavy Chain
20 May 2016
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Immunity to parasites: premunition: parasite held in check by host of persistent latent infection, concomitant immunity: schistosome meaning infected by one parasite = resistant to other parasites of related diseases/parasites, immunology criteria: Macrophages, dendritic cells, and b cells (chicken bursa: b cell: recognizes everything. T cells (thymus): needs help from helper cells/b cells: recognized mhc peptides. Immunology overview: antibody (humoral) and t cell receptor (cell-mediated: t cells) Ige: fights against hemilths and produces allergy symptoms. Tcr: complex: antibody presentation, class i (found in all cell types)/ii mhc"s. Major histo compatability complex: individuality among species. T cells bind to mhc with tcr for peptide recognition. Dendritic cells, b cells, and macrophages: present antigen to t cells. Cd4 (class ii): helper t cells: th1 (primary helper), th2 (human worm infection), and th17 (inflammation) Chronic: bad (body cannot get rid of problem: cytokines: communication chemicals/protein molecules. Cd8 (class i): cytotoxic t cells = kills via granules: macrophages: innate.
