01:146:328 Lecture Notes - Lecture 1: Rna, Macrophage, Desmond Tutu

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Review of last lecture: history, life cycle, diagnosis, pathology, therapy, genome anigenic variaion. Viceral le- fevers, enlargement of sleep and liver. A single gene mutaion in le can make the parasite more temp sensiive. Tf2-ppa gamma ani inlammatory respose- tf2 response- arginase dehydrogenase le happy in lysosomal forms. 2nd exam: gardia- parasiic protozoa- in super group excavata: know which groups the protozoans belong, no mitochondria. 10 cysts ingesions can cause diarrhea: 3-25 days infecion, some gardia afect animals, most commonly reported infecion world wide (200 million, a b c d e f g. Human infecion types from a and b mostly: 500 thousands cases per year. 7% incident rate: 1681- anthony von leeuwenhoek. G. duodenalis- speciic locaion: gr causes malnutriion in kids due to blockage of intesines. Infected wwi soldiers: it has 2 nuclei. All protozoa to atach to surface of something not sure what he said: one cyst has 4 nuclie become 2 protozoa, 4 pairs of lagellum.

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