01:146:328 Lecture Notes - Lecture 6: Paragonimus, Trematoda, Zoonosis

• School: Rutgers University
• Department: Cell Biology and Neuroscience
• Course: 01:146:328
• Professor: A.Keating

Document Summary

Opisthorchis viverrini (the cat liver fluke: life cycle and diagnosis is very similar to c. sinensis. September 14, 2020: cholangiocarcinoma (cca) (1) primarily associated with o. viverrini (2) it is a combination of effects due to: (a) mechanical injury (i) (ii) (iii) (i) (ii) (iii) Eggs trapped in ulcers and induce inflammation (b) toxic metabolic secretions (i) mitogenic stimulate host cell proliferation and eventually become cancerous (ii) may induce transcriptional changes in the host cell (c) immunopathology. Nitric oxide is released by certain immune cells in response to parasite antigens. Excess nitric oxide is thought to be mutagenic and inhibits dna repair. Still fighting: vietnam vets seek help for rare cancer. Years after returning from vietnam, vets are experiencing rare bile duct cancers that may be linked to their service and the uncooked fish they ingested while being there. These worms can develop into cancer if not treated early on.