01:146:295 Lecture Notes - Lecture 11: Lamellar Corpuscle, Postcentral Gyrus, Dorsal Root Ganglion

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Associated with mechanoreceptors of the skin; detect touch and vibration. Associated with pain and temperature detection: mechanoreceptors: associated with a axons; found in the skin. Ruffini"s ending & pacinian corpuscle: deeper in the dermis; detect deep pressure. Meissner"s corpuscle & merkel"s disk: superficial; detect light pressure. Hair follicle receptor: detect insects or anything moving the hair follicle. Extra or intracellular proteins attach to mechanically-gated ion channels na+ and ca2+ enter ion channels trigger ap. Slow: ap fired w/o regard to stimulus: dorsal-column-medial lemniscal pathway: pathway for a axons, carry information about touch to brian; only takes 3 neurons from skin brain. Primary afferent axon: come in through dorsal root dorsal column goes all the way up the spinal cord (ipsilateral - stays on the same side of the spinal cord) synapse at brain stem. Cell body in the brain stem sends axon that crosses midline to opposite side axon goes through thalamus synapse at vp nucleus of thalamus.

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