01:146:245 Lecture Notes - Lecture 11: Lamellar Corpuscle, Dermis, Glabrousness

• School: Rutgers University
• Department: Cell Biology and Neuroscience
• Course: 01:146:245
• Professor: Professor Wilhelms

Document Summary

These are all low threshold, high sensitivity make action potentials with even light stimulation. ~they all have a specific range of frequencies that they respond to. Most common type of mechanoreceptor in glabrous skin (hairless places i. e. palms, soles of feet) Encapsulated, capsule made of lamellae layers of schwann cells. The fibers make up 40% of sensory innervation of hand. The nerve fibers make rapidly adapting action potentials. Also found deep in interosseous membranes (joints) and mesenteries in gut. Has inner core of lamellae and outer lamellae. Inner and outer lamellae separated by a fluid-filled layer. Center of core has rapidly adapting afferent axons. So they can discriminate fine texture, moving stimuli that make high-frequency vibration. Make up 10-15% of receptors in subcutaneous part of hand. ~merkel"s disks cutaneous, in epidermis, aligned with papillae under dermal ridges. Terminal end of the nerve fiber has a wide disk shape that is closely applied to another cell that releases vesicles of peptides.