01:119:195 Lecture Notes - Lecture 14: Amyloid Beta, Extracellular Fluid, Narcolepsy

• School: Rutgers University
• Department: Biological Science
• Course: 01:119:195
• Professor: J.Schjott

Document Summary

All animals sleep eeg patterns detected that indicate sleep. Changes in structure and molecular machinery of synapses during sleep. Memory chains are stored in synaptic connections. Smaller synapses became even smaller during the night. Decreasing synapses at night and taking away the changes occurring. Synaptic connections are altered between sleep and wake states. Homer1 proteins expressed during sleep states keeps memories. Protects neurons from constant activation during wake states. Asleep- more interstitial fluid, better csf flow, clearing wastes. Brain does not have any lymphatic vessels to clear waste. Buildup of amyloid beta cleaned out during sleep state.