01:119:195 Lecture Notes - Lecture 13: Reticular Formation, Retinohypothalamic Tract, Melanopsin
27 Mar 2018
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Document Summary
Wake 1 2 3 4 3 2 1 rem 1 2 3 4 3 2. Sleep is controlled by the combined effects of. Homeostatic drive- the longer you"ve been awake, the more pressure to sleep. Mediated at least in party by adenosine. Regulates what time of day sleep happens. Retinohypothalamic tract is most sensitive to blue light stimulation. Photosensitive ganglion cells contain the photopigment melanopsin (blue line) compared to the natural daylight and artificial light. Blue light indicates brightness level based on sunlight. Blue light seems brighter than other lights which is why it is used in phones, computers etc (459-485 nm) Retina tells scn that it is bright outside melatonin inhibited. Retina tells scn that is dark outside melatonin released. The longer you"ve been awake, the higher levels of adenosine. Adenosine binds to receptors on ras (reticular activating system) neurons that keep you awake and turn them off.
