01:119:150 Lecture Notes - Lecture 11: Thrombus, Malaria, Heme

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The circulatory system ties all the organ systems together. An adult has five liters (11 pints) of blood. Plasma is the yellowish liquid portion of blood. Globulins : transport insoluble or very small molecules. The remaining plasma proteins are involved with blood clotting. Plasma without the clotting factors is serum (e. g. , fibrinogens) Large surface area relative to their volume. Each containing a single iron atom, a heme group. Each heme can bind to one oxygen molecule (o2) Oxyhemoglobin : a bright red substance formed by the combination of. The binding of o2 to hemoglobin occurs only when there are very high hemoglobin with oxygen, present in oxygenated blood levels of oxygen (and a ph that is not very low) When oxygen (and ph) levels are low hemoglobin releases oxygen. After releasing o2, heme groups will bind to carbon dioxide (co2) They attack invading organisms and remove toxins, wastes, and damaged cells.

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