01:119:150 Lecture Notes - Lecture 14: Natural Killer Cell, Complement System, Earwax
27 Apr 2019
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Document Summary
The body has three lines of defense: Tear and saliva enzymes break down bacteria. Mucus (in respiratory, digestive, urinary, and reproductive systems) Pathogens that escape the first line of defense must confront an internal, second nonspecific line of defense. Phagocytes (wbcs) engulf and digest invaders ( phagocytosis) Macrophages move throughout the lymph cleaning up dead and damaged cells. Macrophages also stimulate white blood cell production protozoans and worms. Eosinophils (wbcs) work as a team to secrete digestive enzymes to destroy larger invaders, such as. Natural killer cells (wbc) found in lymph and blood. Attack tumor and virus invaded body cells. Release chemicals that cause their target cells to burst. Interferons are produced by virus-infected body cells to help uninfected cells resist infections. Complement proteins include 20 proteins that help other defense mechanisms. Inflammatory response produces redness, warmth, swelling, and pain. Macrophages release pyrogens , which raise body temperature above normal.
