01:119:116 Lecture Notes - Lecture 25: Vulnerable Plaque, Extracellular Fluid, Coronary Circulation
15 Mar 2016
School
Department
Course
Professor
Document Summary
Dissolved ions: buffer, osmotic balance, interstitial fluid. Plasma proteins: regulate fluid balance between plasma and interstitial fluid, buffers - ph 7. 4, fibrinogens clotting. Serum plasma minus fibrinogens: immunoglobulins antibodies, defense, apolipoproteins lipid transport. Lipids not soluble bound to proteins: albumin regulate ph and fluid balance. Substances being transported: nutrients, wastes, gases, hormones (cid:1) Produced in bone narrow: in ribs, vertebrae, sternum, and pelvis, multipotent stem cells. Differentiate into any type of blood cell: stem cell divides. Stem cell or specialized cell: fig 42. 17. Red blood cells (rbc: erythrocytes, most numerous. 5-6 x10^6 in mm^3: 120 days, flexible biconcave discs. Anaerobic metabolism: specialized o2 transport, hemoglobin. Sensitive to amount of o2 reaching tissues. If not enough o2, kidney produces epo stimulates cells in bone narrow more rbcs. If too much o2, level of epo goes down, production of. Leukocytes: defend against invaders, circulatory system, interstitial fluids, and lymph nodes, 5 major types.
