01:119:116 Lecture Notes - Lecture 7: Fluid Mosaic Model, Integral Membrane Protein, Lipid Bilayer
3 Dec 2017
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Document Summary
Membrane components can move laterally within one layer of the membrane. Fluidity depends on:temp- chain length of tails + bends in tails- saturation- amount of cholesterol acts as a spacer . Membrane proteins- proteins determine many membrane functions- tend to be amphipathic. Integral or peripheral- can move but not flip. But we will focus on: transport, enzymes, signal transduction, others- cell-cell recognition, intercellular joining, attachment to cytoskeleton and ecm. Carbohydrates- polysaccharides attached to protein= glycoprotein or lipid s. Two basic types of transport: passive- doesn"t use metabolic e (atp)- moves with gradient- bike downhill . Includes: simple diffusion, osmosis, facilitated diffusion (uses proteins) Diffusion- tendency for molecules of a substance to fill available space- Osmosis- diffusion of water across selectively permeable membrane. Water diffuses: from lower to higher (solute)- or from higher to lower (h2o) Solvent: a substance capable of dissolving other substances water= the universal solvent. Solute: a dissolved substance- lemonade powder- dissolves in water-
