01:119:116 Lecture Notes - Lecture 21: Sliding Filament Theory, Rigor Mortis, Neuromuscular Junction

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Muscle tissue generates mechanical f in response to nervous sys motor output for ex: locomiotion and manipulation of objects, circulation of blood, feeding and movement of food through digestive tract. 3 types of muscle in vertebrates: skeletal, smooth, cardiac, vertebrate skeletal muscle. Attached to bones by tendons (tough cord sof connective tissue)\most abundant tissue in body. Consist of a bundle of single long cell called muscle fiber, running parallel to the length of the muscle. Each muscle fiber is a bundle of myofibrils: structure of muscle fiber (cell) Multinucleate derived from many cells fused into a giant one. T(transverse) tubules infolding of plasma membrane. Sarcoplasmic reticulum (sr) specialized er of muscle fiber. Myofibrils long fibers run lengthwise through fiber + composed of two types of filaments: thin filaments. 2 strands of actin = contractile protein: actin molecules have myosin-binding sites. Troponin complex = set of regulatory proteins: thick filaments.

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