01:119:115 Lecture Notes - Lecture 13: X Chromosome, Thomas Hunt Morgan, Drosophila Melanogaster
Document Summary
1902: scientists began to develop the chromosome theory of inheritance : genes: have specific loci on chromosomes, chromosomes undergo segregation and independent assortment today genes are locates on chromosomes fig: 5. 12, morgan and the chromosomes theory of inheritance. Evidence that x"s are the location of mendel"s heritable factors : morgan"s choice of experimental organism. Morgan chose to study drosophila melanogaster a common species of fruit fly. A convenient organism for genetic studies: they produce 100s offspring, a generation every two weeks, they have only four pairs of chromosomes. Traits studies in drosophila melanogaster: wild type phenotype for character most commonly observed in population ex: red eyes, mutant phenotype. Ex: white eyes (first mutant found in male: for a given character, gene given symbol for 1st mutant ex: allele for white eyes: w red eyes: w^, correlating behavior of a gene"s alleles with behavior of a chromosome. Morgans experiment: he mated red eye female x white-eyed male.