01:119:115 Lecture Notes - Lecture 6: Lipid Bilayer, Transmembrane Protein, Signal Transduction

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Functions: modifies products of er, manufactures certain macromolecules, sorts and packages materials into transport vesicles, shipping product out of golgi using vesicles, lysosomes. Sacs of powerful hydrolytic or digestive enzymes produced in rough er: primary lysosome. Processed in golgi bud off: secondary lysosome. When primary lysosome fuses with vesicle containing ingested material. Break down complex molecules- make mol. , degrade foreign mol: vacuoles. Large vesicles derived from the er and golgi apparatus. Functions: variety of functions in different cells. Contractile vacuoles: found in many fresh water protists, pump excess water out of cells. Central vacuoles: found in many nature plant cells, hold organic compounds and water. Hydrophobic interactions: form bilayers: fluid mosaic model. Membrane= fluid structure + mosaic of various proteins. Must be fluid to work properly: the fluidity of membranes. Membrane proteins: types: peripheral proteins: on surface of membrane, only hydrophilic. Integral proteins: inside membrane: if span membrane : transmembrane protein, internal hydrophobic/ external hydrophilic membrane.

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