01:119:115 Lecture Notes - Lecture 64: Centriole, Spindle Apparatus, Telophase

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Meiosis reduces the number of chromosomes sets from diploid to haploid. Like mitosis, meiosis is preceded by the replication of chromosomes. Meiosis takes place in two sets of cell divisions, called meiosis i and meiosis ii. The two cell divisions result in four daughter cells. Each chromosome composed of 2 sister chromatids (exact copies) In the first cell division (meiosis i), homologous chromosomes separate. Meiosis i results in two diploid daughter cells with replicated chromosomes. In the second cell division (meiosis ii), sister chromatids separate. Meiosis ii results in four haploid daughter cells. Division in meiosis i occurs in four phases: Prophase typically occupies more than 90% of the time required for meiosis. In synapsis , homologous chromosomes loosely pair up, aligned gene by gene. In crossing over, nonsister chromatids exchange dna segments. Each pair of chromosomes forms a tetrad, a group of four chromatids. Each tetrad usually has one or more chiasmata, x shaped regions where crossing over occured.

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