01:119:115 Lecture Notes - Lecture 16: Genotype Frequency, Allele Frequency, Gene Pool

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Was not aware of mendel"s work on inheritance of traits and that it follows particular pattern. In 1930s/1940s scientist combined principles of mendelian inheritance with. Their synthesis explains variation among organisms in terms of genetic mutations. Synthesis emphasizes genetics of populations as central focus of evolution. A change in allele frequencies in a population over generations. Three main mechanisms can cause allele frequency changes: natural selection, genetic drift, gene flow. Individuals in a population can very in phenotype. Some variation is due to environment (non-heritable variation: example: individual flamingo"s color and caterpillars. Some variation is inherited (heritable variation: example: snails and frogs. Variation in heritable traits is what makes evolution possible. Formation of new alleles (e. g. as a result of mutations- changes in nucleotide sequence) Alterations of gene number or position (often detrimental but not always harmful; e. g duplications can take on new functions with further mutation)

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