01:119:115 Lecture Notes - Lecture 18: Central Nervous System, Axon Hillock, Peripheral Nervous System

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Insulate axons of neurons: regulate extracellular fluid surrounding neurons, 10x to 50x more glia than neurons in mammal brains d. Information processing by nervous system occurs in three stages and by different types of neurons. Figure 48. 4 and 48. 5 process of nervous system: sensory input when sensory neurons transmit information about external stimuli. Ions play an essential role in neuronal signaling a. Stimuli cause membrane potential of neurons to change: change occurs because gated ion channels open or close in response to stimuli. Figure 48. 9 gated ion channels: opening gated k channels in resting neuron causes net k outflow, causes shift in membrane potential towards ek (-90mv) ii. Inside of cell membrane is less negative: simple shifts in membrane potential because of hyper-polarization or depolarization = graded potential, graded potentials have magnitude that varies with strength of stimulus. Figure 48. 11: stimulus opens some gated na channels causing start of depolarization a.

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