01:119:115 Lecture Notes - Lecture 1: Long-Term Potentiation, Long-Term Memory, Cerebral Cortex

• School: Rutgers University
• Department: Biological Science
• Course: 01:119:115
• Professor: Stern Cardinale

Document Summary

Lecture 1 (concept 49. 4 and 1. 1): biology and learning. Ner(cid:448)ous syste(cid:373) neuro(cid:374)s a(cid:374)d supporti(cid:374)g (cid:272)ells: embryonic development controlled by, gene expression. Signal transduction: neuro(cid:374)al plasti(cid:272)ity (cid:894)(cid:373)odifi(cid:272)atio(cid:374) of (cid:271)rai(cid:374) after (cid:271)irth(cid:895) (cid:271)rai(cid:374) is dy(cid:374)a(cid:373)i(cid:272) a(cid:374)d changeable. A(cid:272)ti(cid:448)ity depe(cid:374)de(cid:374)t (cid:894)(cid:373)ore a(cid:272)ti(cid:448)ity (cid:373)ore (cid:272)o(cid:374)(cid:374)e(cid:272)tio(cid:374)s(cid:895) Multiple sy(cid:374)apses a(cid:272)ti(cid:448)atio(cid:374): (cid:373)ore (cid:272)o(cid:374)(cid:374)e(cid:272)tio(cid:374) stre(cid:374)gthe(cid:374) respo(cid:374)se to synapse. Autism: disruption in activity-depe(cid:374)de(cid:374)t re(cid:373)odeli(cid:374)g at sy(cid:374)apses impairment in communication and repetitive behaviors: long term potentiation: transfer of info from short term memory to long term memory, memory: physiological/anatomical event occurring at chemical synapses. Stm: temp, limited, info released if irrelevant, info stored in hippocampus. Ltm: per(cid:373)a(cid:374)e(cid:374)t, i(cid:374)fo retai(cid:374)ed, li(cid:373)itless, (cid:449)he(cid:374) (cid:374)eeded retrie(cid:448)ed i(cid:374)to. Tra(cid:374)s(cid:373)issio(cid:374) of i(cid:374)fo physiologi(cid:272)al (cid:272)ha(cid:374)ges a(cid:374)d use-dependent. Learning: use of memory to lessen negative outcome (evolution product): use of info is a sorting process (important is kept, unimportant is kicked, organization and chunking helps form memories. Evolution: scientific explanation for unity and diversity: living organism: modified descendants from common ancestors.