01:119:115 Lecture Notes - Lecture 15: Thomas Hunt Morgan, Homologous Chromosome, Mendelian Inheritance

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Chapter 15 - the chromosomal basis of inheritance. Morgan traced a gene to a specific chromosome. In the early 20th century, thomas hunt morgan was the first geneticist to associate a specific gene with a specific chromosome. Like mendel, morgan made an insightful choice in his experimental animal. They will be red-eyed if they have a red-eyed allele or white-eyed if they have a white-eyed allele. Sturtevant used recombination frequencies from fruit fly crosses to map the relative position of genes along chromosomes: a genetic map based on recombination frequencies is called a linkage map. Some genes on a chromosome are so far apart that a crossover between them is virtually certain. In this case, the frequency of recombination reaches its maximum value of 50% and the genes behave as if found on separate chromosomes. Concept 15. 3 sex-linked genes exhibit unique patterns of inheritance.

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