11:067:330 Lecture Notes - Lecture 10: Acetyl-Coa, Adipose Tissue, Skeletal Muscle

• School: Rutgers University
• Department: Animal Science
• Course: 11:067:330
• Professor: P Stark

Document Summary

Glucose = most important carb for animal cells. Breaking down of glucose to provide cells with e (atp) Glycolysis 1st step of glucose catabolism. Leads to a small amount of atp, more produced from 2nd step (oxidative phosphorylation) 10 reactions in glycolysis result in breakdown of glucose to pyruvate. Pyruvate 3-c compound: every mole of glucose (6-c) = 2 mol pyruvate. Pyruvate metabolism dependent upon animal and animal"s metabolic condition (resting vs active) Lactate (anaerobic): yields net 2 moles atp per glucose (4 produced, 2 lost) Co2 + h2o (complete oxidation; aerobic): yields net 36 moles atp per glucose. Cell might be a rumen bacterium lives in anaerobic environment. Skeletal muscle may be anaerobic quick, instant contractions (rabbit sprinting from dog) Builds up lactate in muscle: decreases mobility, anaerobic for short distances only. Aerobic cells: pyruvate diffused from cytoplasm into mitochondria. Inside mitochondria, 2 tca cycle intermediates made: acetyl-coa and oxaloacetate (oaa)