PSY-1 Lecture Notes - Lecture 12: Antidepressant, Clozapine, Buspirone
Document Summary
Anti-anxiety drugs designed to reduce anxiety without affecting alertness or concentration. One drawback is psychological and physical dependence. Newer drug called buspirone is slow acting, has fewer fatiguing side effects, and has less potential for abuse. Slows down excitatory synaptic activity by affecting gaba. Antidepressant drugs fall into three major categories: Tricyclics increase activity of excitatory neurotransmitters norepinephrine and serotonin. Monoamine oxidase inhibitors same effect as tricyclics through different method. Reduces activity of monoamine oxidase, an enzyme that breaks down the neurotransmitters. Can cause dangerous elevations in blood pressure when taken with certain foods. Selective serotonin reuptake inhibitors increases activity of only serotonin. Many patients experience nervousness, insomnia, sweating, joint pain, or sexual dysfunction. Gradually replacing tricyclics because of milder side effects and. Antipsychotic drugs have allowed severely disordered people to leave the hospital more rapid reducing of depressive symptoms setting. Reserpine, drug from root of snakeroot plant, found to calm psychotic patients.
