NUR 424 Lecture Notes - Lecture 12: Malignant Transformation, Oncology, Neoplasm
Document Summary
Chapter 15: oncology: nursing management in cancer care, pp. Cancer: disease process, begins when abnormal cells are transformed by genetic mutation of cellular dna, metastasis, abnormal cells have invasive characteristics and infiltrate other tissues, neoplasia, uncontrolled cell growth that follows no physiologic demand. A pattern of growth in which cells lack normal characteristics and differ in shape and organization with respect to their cells of origin. Malignant spread: invasion, refers to the growth of the primary tumor into the surrounding host tissues. Pressure of a rapidly growing tumor may facilitate the invasion into the blood or lymph nodes. Angiogenesis growth of new blood vessels cancer can use to spread. Lymph nodes: metastasis, dissemination or spread of malignant cells from the primary tumor to distant sites by direct spread of tumor cells to body cavities or through lymphatic and blood circulation. Carcinogenesis: malignant transformation, three step cellular process.
