NUR 326 Lecture Notes - Lecture 7: Agranulocytosis, Perspiration, Indole

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21 Mar 2017
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Glossary: phagocytosis, tinnitus, helicobacter pylori, guiac/hemiccult, hematemesis, vasodilation, steven-johnson syndrome/toxic epidermal necrolysis, paresthesia, hyperthermia, diaphoresis, myelosuppression, thrombocytopenia, agranulocytosis, myasthenic. Nonpharmacological treatments for persistent pain in older adults: general nonpharmacologic approaches. Nsaids non salicylates: non-selective (cox-1 and cox-2, selective (cox-2, disease/condition specific drugs. Anti-inflammatory medications (glucocorticoids = corticosteroids = steroids: salicylates and salicylate derivatives, nsaids, propionic acids, fenamates, oxicam derivatives, cyclooxygenase-2 inhibitors, drugs used in treatment of specific conditions: Immunosuppressive: gold compounds, tumor necrosis factor blockers, others. Nsaids salicylates and related: acetylsalicylic acid (asa, aspirin) Nsaids non salicylates: non-selective (cox-1, cox -2) Ibuprofen (motrin, advil: naproxen (naprosyn, aleve, ketorolac. Indomethacin (indocin: selective (cox-2, celecoxib (celebrex, topical, diclofenac gel, disease/condition-specific drugs. Redness (accumulation of blood at site of injury) Swelling/edema (kinins/histamines dilate arterioles; increase capillary permeability; plasma leaks into tissue) Warmth and pain (increased blood flow, swelling and chemical mediators) Loss of function (fluid, pain, swelling, decreased mobility: prostaglandins vasodilation, increased capillary permeability, sensitization of nerve cells.

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