NUR 326 Lecture Notes - Lecture 4: Adrenergic Agonist, Bronchospasm, Peanut Allergy
Document Summary
Bronchodilators/antiasthmatics: xanthine"s dilates airways (drugs end in ylline, aminophylline, use usually reserved for acute bronchospasm emergency, theophylline, relaxes smooth muscle of bronchi, bronchioles promoting bronchodilation, relief/prevention of asthma, reversal of bronchospasm b/c copd, low therapeutic index (10-20mcg/ml) 20 25 start to see adverse effects. 30-35 hyperglycemia, hypotension, cardiac arrhythmias, tachycardia, seizures, brain damage, death: many drug interactions, caffeine can increase levels. Direct effect on the smooth muscle of the bronchioles. Symptomatic relief or prevention of bronchial asthma and for reversal of bronchospasm associated with copd. Contraindicated in coronary disease, respiratory dysfunction, renal or hepatic impairment. Adverse effects tachycardia, seizure, brain damage, and death. Acute asthma, bronchospasm in acute or chronic asthma, prevention of exercise induced asthmas. Adverse effects stimulation of heart, cns. Anticholinergics patients who cannot tolerate sympathetic effect of the sympathomimetic (dilator due to effect on vagus nerve: ipratropium (atrovent) Dose = 3-6 puffs four times daily. Ask about peanut allergies: tiotropium (spiriva)
