ANSC 23000 Lecture Notes - Lecture 4: Haemophilus Influenzae, Oral Mucosa, Microbiota
27 Sep 2018
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Document Summary
Immunology: study of the body"s defense against infection. Immunity: ability of an organism to resist a particular infection or toxin. Autoimmunity: system of immune responses of an organism against its own healthy cells and tissues. Microbiome: microbes in the tissues, skin, oral mucosa, and gi tract that cause no damage to the host organism. Ex. viruses, parasites, bacteria, toxins: extracellular: pathogen that can replicate outside the cell. Do not invade cells and proliferate in the extracellular environment. Some don"t even penetrate body tissues but adhere to epithelial surfaces and cause disease by secreting toxins. Can"t survive in intracellular environment or induce their uptake into host cells. Haemophilus influenza, e. coli, pseudomonas aeruginosa, staph aureus, vibrio cholerae. Intracellular: pathogen that requires cellular environment to replicate. Either invade host cells when it gives them selective advantage in the host or can"t survive outside the host at all. Can only be eliminated by a cellular immune response.
