MICRB 201 Lecture Notes - Lecture 1: Actin, Active Transport, Cell Membrane
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Note: hooke was the first microscopist to study living matter. Van leeuwenhoek"s observation revived theory of spontaneous generation: )nitial evidence in mid (cid:883)8(cid:882)(cid:882)"s role of fungi in causing silkworm disease and. His experiments finally dispelled theory of spontaneous generation. Provided indirect evidence (1840-60s) that microbes cause human disease: showed that antiseptic agents (e. g. heat, phenol) that kill microbes also prevent post-surgical infections (origin of antiseptic surgery) By study of anthrax, provided conclusive and direct evidence that. )n the process, developed the germ t(eory of d)sease or koc("s: microbe must be present in all cases of disease and absent from. Postulates healthy organisms: putative pathogen (pathology generator) must be isolated and grown in pure culture. Growth of bacteria on solid media: isolated organism must cause same diseases in a healthy host, same organism must be isolated again from newly diseased host. Development of the petri dish by richard petri. About 20 elements found in living organisms (figure a1. 1)
