B M B 211 Lecture Notes - Lecture 17: Proteolysis, Ketogenesis, Ketone Bodies

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With the exception of youth, illness, or pregnancy, the body strives to maintain metabolic steady state. We do not need to constantly eat to maintain this balance. The postprandial state occurs just after a meal has been digested or absorbed. Sugars and amino acids are absorbed directly into the blood from the small intestine. Lipids are transferred via chylomicrons to muscle or adipose tissues for storage. Any leftover lipids are sent to the liver. As (cid:271)lood sugar rises, the -cells of the pancreas release insulin, a 51 amino acid polypeptide. Insulin decreases breakdown of stored fuel while promoting fuel storage. Fatty acid synthesis in the liver and adipose tissue. Transportation of amino acids into cells to stimulate protein synthesis. Metabolism in a healthy individual after a well-balanced meal. The early post-absorptive state begins as the nutrients flow from the intestine ends.

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