MICR 2123 Lecture Notes - Lecture 11: Uracil, Arginine, Thymine

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Biosynthesis, or anabolism, is the building of complex biomolecules. Biosynthesis requires: essential elements: c, h, o, n, and other essential elements. In autotrophs, comes from an inorganic source (co2) These organisms need to fix carbon into an organic form to be able to use it for biosynthesis (co2 fixation) Some organisms are capable of fixing n2 into organic compounds: reduction: by a reducing agent such as nadph, energy: mainly in the form of atp hydrolysis. Co2 fixation by autotrophs - converted to an organic form of carbon. Fatty acid biosynthesis- building blocks of cell membrane and cell lipids. N2 fixation- converted to an organic form of n2 (nh3) Amino acid biosynthesis- building blocks of proteins. Purine and pyrimidine biosynthesis- building blocks of nucleotides and eventually dna and rna. Also called the reductive pentose phosphate cycle. Requires tremendous input of energy and reduction. Who does it: oxygenic phototrophic bacteria (cyanobacteria, chloroplasts of algae and plants, others.

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