PSYCH 3313 Lecture Notes - Lecture 22: Granule Cell, Red Nucleus, Cerebellum

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Habituation in aplysia annoying stimuli: less glutamate released onto motor neuron, short-term habituation at the synapse, repeated stimuli to siphon, sensory neuron releases less neurotransmitter, motor neuron releases less neurotransmitter, gill shows weak withdrawal. Long-term habituation and sensitization at the synapse: can last up to 3 weeks (not just neurotransmitter depletion, long-term habituation. Cerebellar circuits and classical conditioning: purkinje cells. Purkinje cells, or long-term depression (ltd: this reduces the inhibition of the lateral interpositus neurons leading to increased activation to the cs. Reversible lesions of the lateral interpositus nucleus impair conditioning: red nucleus = projects to facial and abducens controlling reflexive eyeblink, lateral interpositus nucleus = important for learning eyeblink conditioning. Trace conditioning paradigms: delay conditioning, the cs overlaps the ucs, no stimulus-free interval, trace conditioning, the cs and the ucs do not overlap, a stimulus-free interval occurs, requires the participation of forebrain areas, requires conscious, declarative processes.

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