NURSE-UN 1436 Lecture Notes - Lecture 4: Atrial Flutter, Cardiac Muscle Cell, Resting Potential
14 Nov 2018
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Dysrhythmia, drugs that can prolong qt interval. Week 4: cv agents part ii: amiodarone, erythromycin, ciprofloxacin, clarithromycin, cisapride, droperidol, famotidine pepsin, haloperidol ix) lithium, methadone xi) octreotide xii) pentamidine xiii) Slows the recovery of the cells slowing of conduction and automaticity. Blocks k+and slows the upward movement of k+ during phase 3 of the ap; prolongs the repolarization, slows the rate & conduction of the heart. Structurally similar to th (1) slows down the relaxation, increase a bit of co and delays conduction: uses: vtach/fib, atrial flutter/fib. Think ccb: uses: vtach/fib, atrial flutter/fibrillation and psvt. At the renal level it produces retention of na+ and water, resulting in an in preload and afterload, edema formation and the appearance of symptoms of pulmonary and systemic venous congestion. In addition, it the elimination of k+ and magnesium, creating an e+ imbalance which may be responsible in part for cardiac arrhythmias.
