BIOL 3320 Lecture Notes - Lecture 2: Earwax, Hemoglobin, Dendritic Cell
Document Summary
The integument largest body system of the body. Protection - of the underlying tissues and organs. Stratum corneum the lipids are outside of the cell so water can"t enter. Epidermis micrograph of thin skin micrograph of thick skin (the palms and hands of the feet has 5 layers. Stratum basale is attached to the basement membrane by hemidesmosomes has many basal cells. Keratinocytes produce brous protein keratin most cell of epidermis tightly connected by desmosomes. Ex: melanoma- most deadly, happens in sun exposed area. Melanin is the only pigment made in skin produced in melanocytes under uv light exposure. Freckles and pigmented moles (only some melanomas change our pigment) Carotene: yellow to orange pigment most obvious in palms and soles accumulates in stratum corneum and hypodermis. Hemoglobin pinkish hue of fair skin di erent than jaundice, look at the eyes. Vitamin d3 epidermal cells produce cholecalciferol liver and kidney convert vitamin d3 into calcitrol important for calcium and phosphate.
